This paper represents a clinical study of 228 children coming under our observation during the past two years as volunteer workers in the Saturday morning children's clinic of the tuberculosis division of the Seattle Department of Health. It should be understood at the outset of this paper that these children represent a group in the community most likely to give evidence of tuberculous infection, since the large majority are children from tuberculous homes. Many other children were seen who cannot be included in this series owing to the incompleteness of their records. The reasons for this are unavoidable, since many children come to the clinic but once, and no opportunity is given either for the observation of the von Pirquet test or to confirm any conclusion reached at the time of the first visit. For purposes of convenience in the filing and handling of records in the clinic some definite
MANNING JB, KNOTT HJ. A CLINICAL STUDY OF TWO HUNDRED AND TWENTY-EIGHT CHILDREN IN RELATION TO TUBERCULOUS EXPOSURE CONTROLLED BY VON PIRQUET REACTION. Am J Dis Child. 1915;X(5):354–359. doi:10.1001/archpedi.1915.04110050043004
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