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Clinical Department
June 1916


Author Affiliations

Resident Physician, The Children's Memorial Hospital CHICAGO

Am J Dis Child. 1916;XI(6):460-461. doi:10.1001/archpedi.1916.04110120057005

The following clinical history is that of a child, who, during an attack of bronchopneumonia, developed a generalized streptococcic infection. This was exhibited clinically by the almost simultaneous appearance of a purulent arthritis, erythema nodosum and erysipelas. A streptococcus was cultivated from the blood, from a joint effusion, and from an excised nodule.

A suspension of the organism from these three sources was injected intravenously into three rabbits. Those receiving the bacterial growth obtained from the excised node and from the joint effusion died within forty-eight hours from septicemia. The rabbit which received the streptococcus isolated from the patient's blood was killed on the fifth day after injection. The right ankle joint was swollen and contained purulent fluid. Cultures from this joint gave a streptococcus.

CLINICAL CASE HISTORY  E. O., boy, 17 months old, was admitted to the Children's Memorial Hospital, service of Dr. F. S. Churchill, Dec. 27, 1915.

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