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August 1916

OBSERVATIONS ON THE TENDENCY OF THE DIPHTHERIA BACILLUS TO LOCALIZE IN THE UPPER RESPIRATORY TRACT: THE IMPORTANCE OF THIS FACT IN ROUTINE CULTURE WORK

Am J Dis Child. 1916;XII(2):149-151. doi:10.1001/archpedi.1916.04110140042006
Abstract

Because of past experiences in finding that the organisms of diphtheria may be present in the larynx and absent in cultures taken from the nose and throat, or positive in the nose and absent in the throat, and so on, at the suggestion of Dr. Cowie I have made a number of observations with this point in view.

Of the eight cases which I wish to report, the organisms confined themselves to one locality in five cases, which I classify as Group 1; to more than one locality in three cases, which I classify as Group 2. GROUP 1

Case 1.  —Ione O., aged 25, with marked clinical unitonsillar diphtheria, entered the hospital Feb. 8, 1916. Diphtheria organisms were present in every culture taken from the right tonsil, absent from every culture taken from the left tonsil and pillars, the pharyngeal wall and lateral bands and from the nose. A

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