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September 1916


Author Affiliations

From the Children's Medical Department, Massachusetts General Hospital.

Am J Dis Child. 1916;XII(3):235-243. doi:10.1001/archpedi.1916.04110150033003

There have been two antagonistic theories advanced to explain the mode of the infection of the kidney in pyelitis of infancy. One theory maintains that the infection of the kidney takes place by the ascending route, through urethra, bladder and ureters; the other, that the infection comes by means of the blood and lymphatics. Before discussing the relative merits of these two theories certain facts in regard to pyelitis as it occurs in infants need to be noted. The disease is much more common in girl than in boy infants, the proportion being nearly three to one. The organism most frequently causing the disease is the colon bacillus, which is the offender in from 50 to 90 per cent. of cases. The pathology of the condition is well established. In uncomplicated cases the pelvis of the kidney is the only portion of the urinary tract involved, and there the local

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