Immunologic studies have illuminated both bacteriology and serology by proving that the majority of pathogenic bacteria belong to groups composed of various types which may be identified by their reactions in the serum of infected animals. Dochez and Gillespie1 showed that the pneumococcus group comprises four types which have since been found in Germany as well as in this country. Two additional types of pneumococci apparently exist in South Africa.2 Types 1, 2 and 3 have definite immunity reactions identical to all members of the group, while Type 4 comprises a number of independent varieties differing from Types 1, 2 and 3 and also from each other. Pneumococci of Type 4 are ordinarily present in the mouth in healthy persons who have not been in contact with lobar pneumonia patients, and cause only 20 to 25 per cent. of the disease. While pneumococci of this type may be
WOLLSTEIN M, BENSON AW. TYPES OF PNEUMOCOCCUS FOUND IN THE PNEUMONIAS OF INFANTS AND YOUNG CHILDREN. Am J Dis Child. 1916;XII(3):254–265. doi:https://doi.org/10.1001/archpedi.1916.04110150052005
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