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Nov 2012

Long-term Outcomes in Children With Pleural Empyema

Author Affiliations

Author Affiliations: Divisions of Emergency Medicine (Dr Florin), Hospital Medicine (Dr Shah), and Infectious Diseases (Dr Shah), Cincinnati Children's Hospital Medical Center; and Department of Pediatrics, University of Cincinnati College of Medicine (Drs Florin and Shah), Cincinnati, Ohio.

Arch Pediatr Adolesc Med. 2012;166(11):1069-1071. doi:10.1001/archpediatrics.2012.1713

For most acute infectious diseases, studies exploring short-term outcomes, such as hospitalization rate, length of hospital stay, time to resolution of symptoms, and trends in laboratory markers of infection, are ubiquitous. These immediate outcomes are important to consider when examining the comparative effectiveness of existing therapies or the development of novel therapeutics. However, there is a paucity of data regarding the longer-term outcomes of acute infections. In this issue of the Archives of Pediatrics & Adolescent Medicine, Cohen et al1 present a prospective observational study of children with pleural empyema, a condition in which pus accumulates in the pleural space, with the goal of examining longer-term outcomes including health-related quality of life (HR-QOL). While some of the longer-term outcomes of infections such as meningitis and otitis media have been explored, to our knowledge, this study is one of the few to describe such outcomes of pediatric empyema.