The existence of the condition termed chorea has been well known ever since the Middle Ages. For centuries the medical profession has endeavored to treat it satisfactorily, as well as to explain its etiology. The results so far have been disappointing. Sedatives, such as bromids and chloral, the salicylates, rest, hydrotherapy, and hygienic measures, all have a beneficial influence on certain symptoms in chorea. Arsenic, however, in this condition is a greatly overestimated drug; I have yet to see it relieve, even in the slightest degree, the choreic manifestations or shorten the course of the disease. We are still sadly in want of a specific remedy to cope satisfactorily with this annoying, chronic, and occasionally serious malady.
In the absence of positive knowledge as to the causation of chorea, it is justifiable to attempt symptomatic treatment alone, with the view of lessening the severity and frequency of the choreic manifestations
HEIMAN H. THE EFFECT OF SUBCUTANEOUS INJECTIONS OF MAGNESIUM SULPHATE IN CHOREA. Am J Dis Child. 1916;XII(2):109–111. doi:10.1001/archpedi.1916.04110140002001
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