[Skip to Navigation]
April 1918


Author Affiliations

Consulting Physician and Physician-in-charge, respectively, of the Children's Hospital Emma AMSTERDAM, HOLLAND

Am J Dis Child. 1918;XV(4):249-258. doi:10.1001/archpedi.1918.04110220002001

During the last year we had the opportunity to observe at least two cases which presented the clinical picture of splenomegaly of Gaucher's type. The family history runs as follows:

Case 1.  —The first child of the family, a boy, 2 years of age, was taken into the hospital in 1901; death soon occurred. To our regret, no clinical history was at our disposal, but the diagnosis, "hepatitis," made at that time, gives us reason to believe that the child had an enlarged liver.

Case 2.  —The second child, a brunette, 11 years of age, was admitted to the hospital for the first time in 1912. The skin, slightly yellow tinted, did not show any signs of marked jaundice. The spleen, distinctly enlarged, was hard and smooth, not painful on palpation; the liver was enlarged, especially the left lobe felt remarkably firm; no ascites; the urine contained small traces of

Add or change institution