In pathogenesis, chloroma is closely related to leukemia, so that although the former is regarded by some authors as belonging to the malignant tumor group, it is now generally accepted that chloroma is an atypical form of leukemia. It is well known that the exact clinical diagnosis of chloroma is sometimes extremely difficult. In our case it seems probably justifiable to consider the disease as myeloblastchloroleukemia, but from the clinical point of view, without performing necropsy, we think it may be proper to call it an acute myeloblastleukemia, with the accompaniment of a chloroma-like tumor in the skull.
REPORT OF CASE
History.—A boy aged 5 years and 9 months, with a negative family history, entered the hospital Dec. 13, 1915. Two years previously, he had had acute nephritis and in the previous May, whooping cough, followed by diphtheria and measles, successively. The onset of the present illness was ten