Since the beginning of the use of insulin, it has been possible for children with diabetes to approach the status of normal children, in contrast to the marked retardation of development shown previous to its use. A study of the physiologic progress of children suffering with diabetes under the modern regimen should furnish valuable information, and determine whether it is possible for these children to attain maturity with a normal physique.
The information obtained from such a study of the diabetic child should be applicable also to problems concerning the nutrition and development of the nondiabetic child. When the normal person is studied, his many compensatory mechanisms will often mask a response which would be obvious if his margin of metabolic balance were reduced to the minimum, as is the case in children with diabetes. It is well known that children suffering with diabetes, if untreated, react rapidly to adverse