Diseases arising during the first years of life may leave their marks on the patient to a higher degree than diseases acquired later in life. That this applies to rickets is a well known fact; less recognized is the fact that tetany, the eclampsia of infancy, may also be the cause of calamitous permanent abnormalities. If the anomaly of metabolism which is manifest in tetany is allowed to persist for a considerable time during the period when the pyramidal cells and other constituents of the brain are forming and developing, it may result in permanent mental defects. This has previously been pointed out in several investigations in Germany and Norway (Carl Looft), and recently Hendriksen1 obtained the same result in his follow-up examination of such patients from the Rigshospital who had reached the age of from 11 to 15 years, for more than half of these children were classified
BLOCH CE. EFFECTS OF DEFICIENCY IN VITAMINS IN INFANCY: CARIES OF THE TEETH AND VITAMINS. Am J Dis Child. 1931;42(2):263–278. doi:10.1001/archpedi.1931.01940140003001
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