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Article
April 1934

HYPOPHYSEAL INFANTILISM: TREATMENT WITH AN ANTERIOR HYPOPHYSEAL EXTRACT: PRELIMINARY STUDY

Author Affiliations

SANTA BARBARA, CALIF.; NEW YORK

Am J Dis Child. 1934;47(4):719-736. doi:10.1001/archpedi.1934.01960110002001
Abstract

Webster defines a dwarf as "a diminutive human being"; Dorland, as "an abnormally undersized person." Turning to a definition of infantilism, one finds that it is "a condition in which the characters of childhood persist in adult life. It is marked by mental retardation, underdevelopment of the sexual organs and often, but not always, by dwarfness of stature." There follows a formidable classification.

In this article, we wish to discuss a type of arrested development presumably due to secretory deficiency of the anterior hypophysis. It is not mentioned by Dorland. With no claim to originality but because of the etiologic and descriptive significance of the term, we have chosen to call the condition hypophyseal infantilism. If one is to escape ambiguity, however, it had best be called dwarfism, since sufferers from this disorder are rarely mentally retarded. That they never become mentally mature, as regards the things which touch on

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