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December 1950

LIVER STEATOSIS IN UNDERNOURISHED CHILEAN CHILDREN: I. Its Evolution as Followed by Serial Puncture Biopsies

Author Affiliations

From the Hospital de Niños Manuel Arriarán and Cátedras de Pediatría of Prof. A. Baeza Goñi and J. Meneghello, Universidad de Chile.

AMA Am J Dis Child. 1950;80(6):889-897. doi:10.1001/archpedi.1950.04040020904001

MALNUTRITION varying intensity in the organism of a child. These alterations are generally in direct relation to the intensity and type of the dietary deficiency and are usually looked for in those organs most accessible to clinical exploration, such as the skin, its appendages and the mucosa of the mouth or eyes. Some research workers1 have been interested in morphological changes of the viscera in patients studied post mortem, but many of these changes, like fatty degeneration and cloudy swelling, cannot always be attributed to a deficient nutritional status. Instead, they may be the consequence of infections which commonly have been the immediate cause of death. However, little is known of the morphology of the internal organs in undernourished children during the reversible period, in which nutritional damage has not been sufficiently intense to bring about death. Thus, it was very important when the Gillmans2 introduced the puncture

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