A previously well 7-month-old male infant presented to our emergency department with 1 week of loose stools, 4 days of fever up to 39.2°C, and 2 days of skin rash. His parents reported several pink papules that first appeared on his trunk and spread to his extremities within 24 hours. His increasing irritability and poor oral intake led to his admission for further evaluation. The patient’s vaccinations were up to date. He had no history of perinatal infections, sick contacts, recent travel, or pets. The family lives in an apartment in New York City.