Antenatal Acetaminophen Use and Attention-Deficit/Hyperactivity Disorder: An Interesting Observed Association But Too Early to Infer Causality

Attention-deficit/hyperactivity disorder (ADHD) is the most common childhood-onset neurodevelopmental disorder. Although it is highly heritable, ADHD has a complex etiology, and noninherited factors also contribute.¹ Early environmental exposures that may cause neurobiological dysfunction and confer risk for ADHD (eg, lead and other toxins) have been gaining increased attention of late.¹