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April 2014

Antenatal Acetaminophen Use and Attention-Deficit/Hyperactivity Disorder: An Interesting Observed Association But Too Early to Infer Causality

Author Affiliations
  • 1Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, Wales
  • 2MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, Wales
  • 3Cardiff University School of Psychology, Cardiff, Wales
JAMA Pediatr. 2014;168(4):306-307. doi:10.1001/jamapediatrics.2013.5292

Attention-deficit/hyperactivity disorder (ADHD) is the most common childhood-onset neurodevelopmental disorder. Although it is highly heritable, ADHD has a complex etiology, and noninherited factors also contribute.1 Early environmental exposures that may cause neurobiological dysfunction and confer risk for ADHD (eg, lead and other toxins) have been gaining increased attention of late.1