The PDR in and of itself does not establish a standard of care or whether a physician adhered to a particular standard; only expert testimony can do that. The PDR is used by attorneys as a resource to support testimony that a certain adverse effect can occur with a drug and that the manufacturer or physician knew or should have known about it. It is most useful as an impeachment tool if a pharmaceutical manufacturer or physician denies knowledge of a particular adverse effect or disputes the existence of the adverse effect. While I am sympathetic to the authors' view that the PDR may receive inappropriate emphasis in a particular legal proceeding, its use is limited to supporting an opinion about the appropriateness of prescribing a particular drug. Any defendant can make the arguments set forth by the authors to try to convince the jury that the PDR is not the "Bible."
Kidwell RP. The Physicians' Desk Reference Should Not Be Held as a Legal Standard of Medical Care—Reply. Arch Pediatr Adolesc Med. 1998;152(6):610. doi:
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