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November 2014

Single vs Multiple Embryo Transfer: Comparative Costs and a Call for Change

Author Affiliations
  • 1Robert Wood Johnson Clinical Scholars Program, Department of Veterans Affairs, University of Pennsylvania, Philadelphia
  • 2Department of Business Economics and Public Policy, Wharton School of the University of Pennsylvania, Philadelphia
JAMA Pediatr. 2014;168(11):997-998. doi:10.1001/jamapediatrics.2014.1683

The equivalent efficacy and superior safety of elective single embryo transfer (SET) compared with elective multiple embryo transfer (MET) after in vitro fertilization (IVF) has been established in recent medical literature. The transfer of a single high-quality embryo selected from a larger number of available embryos after IVF does not decrease implantation rates compared with MET and decreases the rate of twins from 30% to between 1% and 2%.1

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