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Comment & Response
March 2015

Physical Activity and Depression: Type of Exercise Matters

Author Affiliations
  • 1Universidad Europea and Research Institute of Hospital 12 de Octubre (i+12), Madrid, Spain
  • 2Department of Physiology, Faculty of Medicine, University of Valencia, Fundación, Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain
JAMA Pediatr. 2015;169(3):288-289. doi:10.1001/jamapediatrics.2014.3501

To the Editor In the longitudinal study by Toseeb et al1 recently published in JAMA Pediatrics, the authors showed no association between objectively assessed physical activity (PA) and the development of depression symptoms in 736 adolescents across a 3-year period. These important findings are in apparent disagreement with previous interventional research relying mostly on short-term interventions with smaller cohorts and that use self-reported measures of PA.2 Notwithstanding the merit and methodological strengths of the study by Toseeb et al, we believe some clarifications are needed regarding a few potential confounding factors that were not controlled for.