In Reply In a study published in the December 2015 issue of JAMA Pediatrics,1 we aimed to document concussion-like symptoms in high school athletes with no recent concussion during their preseason baseline evaluation and identify health history variables associated with symptom reporting. We reported that concussion history was associated with concussion-like symptoms in high school athletes, but its effect was small relative to certain preexisting learning, psychiatric, and headache disorders. In a letter to the editor,2 Mr Comrie proposed that prior concussion(s) and/or repetitive head trauma through participation in collision sports may be responsible for both the symptoms and the preexisting conditions themselves, suggesting that the effect of prior (documented or undocumented) neurotrauma may be much larger than represented in our study.