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December 2016

Clarifying the Role of Corticosteroids in Kawasaki Disease

Author Affiliations
  • 1Rheumatology Program, Department of Pediatrics, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts
JAMA Pediatr. 2016;170(12):1140-1142. doi:10.1001/jamapediatrics.2016.2307

Corticosteroids and Kawasaki disease (KD) have had a complicated relationship. Sentiment has fluctuated between the extremes, from indispensable to proscribed, even as the roles of intravenous immunoglobulin (IVIG) and aspirin have been defined. As the meta-analysis by Chen et al1 in this issue of JAMA Pediatrics demonstrates, the findings of recent studies are finally lending some clarity to when steroids can be beneficial in KD.