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In 2010, 14.9 million infants worldwide were born premature (less than 37 weeks’ gestation), representing 11% of all newborns.1 Despite many advances made during the past 3 decades in the field of neonatal medicine, preterm birth still presents the second largest cause of death in children younger than 5 years of age.2 Thus, improving the outcomes of preterm infants through the development of refined physiological support systems has been strongly advocated as a part of the United Nations pivotal Millennium Development Goals for child survival.3
Zivanovic S, Roehr CC. One Step Further Toward Defining the Optimal Respiratory Care Package for Neonates: Interventions to Successfully Extubate Preterm Infants. JAMA Pediatr. 2017;171(2):120–121. doi:10.1001/jamapediatrics.2016.3271
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