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In Reply In response to the letters received by JAMA Pediatrics regarding our findings on acetaminophen use, we highlight that we refrained from using the term significant throughout the article because according to the American Statistical Association, “well-reasoned statistical arguments contain much more than the value of a single number and whether that number exceeds an arbitrary threshold. The ASA [American Statistical Association] statement is intended to steer research into a ‘post P <.05 era.’”1
Stergiakouli E, Thapar A, Davey Smith G. Acetaminophen in Pregnancy and Adverse Childhood Neurodevelopment—Reply. JAMA Pediatr. 2017;171(4):396–397. doi:10.1001/jamapediatrics.2016.5040
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