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Comment & Response
June 2017

Influenza Vaccination in the First Trimester of Pregnancy and Risk of Autism Spectrum Disorder

Author Affiliations
  • 1Simpson University, Redding, California
JAMA Pediatr. 2017;171(6):600. doi:10.1001/jamapediatrics.2017.0734

To the Editor The JAMA Pediatrics article by Zerbo et al1 reported a statistically significant association between the administration of the maternal influenza vaccine in the first trimester of pregnancy and the incidence of autism spectrum disorder. The authors stated that the analysis adjusted for covariates yielded a P value of .01 when applying a Cox proportional hazards regression model to the data.

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