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Comment & Response
October 2017

Influenza A Infections in Infants of Vaccinated and Unvaccinated Mothers

Author Affiliations
  • 1Nepean Hospital, Terrey Hills, New South Wales, Australia
  • 2Discipline of Paediatrics, Sydney Medical School Nepean, University of Sydney, Sydney, Australia
JAMA Pediatr. 2017;171(10):1014-1015. doi:10.1001/jamapediatrics.2017.2391

To the Editor We read with interest the article by Hviid et al1 showing influenza A (H1N1) pdm09 vaccine to be safe for use during pregnancy. There has been a reduced risk for influenza and influenza-like illness observed among the infants of vaccinated mothers,2 thought to be owing to transplacental transfer of maternal antibodies.3 Do the data allow comparison of influenza A infections in the offspring between the mothers who have been vaccinated and unvaccinated? This would be of interest because influenza infections are associated with excess morbidity including excess hospitalizations.4

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