A 5-year-old white girl presented with a history of recurrent fevers and urticaria since 2 months of age. The child had fevers (maximum temperature, 40°C) that lasted 3 to 5 days. Her mother reported that the fevers resolved spontaneously but continued to recur almost every month. The fever symptoms were associated with bilateral conjunctivitis, arthralgias, and irritability. The hivelike, nonpruritic urticaria did not improve with antihistamine medication and there were no known precipitating or aggravating factors. The child did not attend day care. Family history was noncontributory and her parents denied consanguinity.
Sukumaran S, Vijayan V. Infantile-Onset Fever and Urticaria. JAMA Pediatr. 2017;171(11):1122–1123. doi:10.1001/jamapediatrics.2017.2531
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