For decades, a variety of general anesthetics and sedatives have been used in pediatric medicine with the goal of providing safe and effective care to children during painful and/or uncomfortable procedures. This practice was believed to be innocuous until animal research over the past 20 years brought an uncomfortable realization to our attention: commonly used general anesthetics and sedatives may have a detrimental effect on immature brain development with long-lasting consequences on cognitive and behavioral outcomes.
Jevtovic-Todorovic V. Anesthetics and Cognitive Impairments in Developing ChildrenWhat Is Our Responsibility?. JAMA Pediatr. Published online October 02, 2017. doi:10.1001/jamapediatrics.2017.3033
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