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February 2018

Reducing the Underimmunization of Transplant Recipients

Author Affiliations
  • 1Adult and Child Consortium for Health Outcomes Research and Delivery Science, Aurora, Colorado
  • 2Section of Gastroenterology, Hepatology and Nutrition, Children’s Hospital Colorado, Aurora
  • 3Department of Medical Ethics, The Children’s Hospital of Philadelphia, Pennsylvania
  • 4Department of Pediatrics, Medical Ethics and Health Policy, Perelman School of Medicine, Philadelphia, Pennsylvania
  • 5Department of Pediatrics, University of Colorado, Aurora
JAMA Pediatr. 2018;172(2):111-112. doi:10.1001/jamapediatrics.2017.3990

Vaccine-preventable infections (VPIs) are a common and serious complication after pediatric liver transplantation; in the first 2 years after transplant, 1 of 6 transplant recipients requires hospitalization for VPI, which is associated with graft injury, morbidity, and sometimes mortality.1 These hospitalizations can increase the cost of the transplant-associated hospitalization by $70 000.1