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Comment & Response
September 2018

Need for Further Analysis in Cognitive Outcomes of Children Born Preterm

Author Affiliations
  • 1Nantong University, Nantong City, Jiangsu Province, China PR
  • 2Affiliated Hospital of Nantong University, Nantong City, Jiangsu Province, China PR
JAMA Pediatr. 2018;172(9):888. doi:10.1001/jamapediatrics.2018.1625

To the Editor We read with interest the large and impressive meta-analysis by Twilhaar et al1 assessing cognitive outcomes of children born preterm and associated risk factors.1 The authors concluded that extremely or very preterm (EP/VP) children had large deficits in intelligence and that bronchopulmonary dysplasia (BPD) was a crucial factor for cognitive outcome. However, we would like to highlight a few important issues regarding the analysis and conclusions.