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JAMA Network Clinical Guideline Synopsis
November 2018

Screening and Management of High Blood Pressure in Children and Adolescents

Author Affiliations
  • 1Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
JAMA Pediatr. 2018;172(11):1087-1088. doi:10.1001/jamapediatrics.2018.2882

Atherosclerosis begins in childhood and is associated with numerous cardiovascular risk factors, including hypertension.1 Pediatric hypertension is associated with cardiovascular target organ damage, which in turn is associated with cardiovascular disease (CVD) events in adulthood.2 Reversal of cardiac target organ damage has been demonstrated with antihypertensive therapy in adults and children,3 and lower left ventricular mass in adults is associated with reduced CVD.4 Pediatric hypertension demonstrates tracking into adulthood.5 Despite these risks and outcomes, pediatric hypertension frequently remains unidentified.6

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