Although long-term survival in children with acute lymphoblastic leukemia (ALL) now exceeds 90%, survivors are at risk for treatment-related neurocognitive dysfunction that can persist into adulthood.1,2 We hypothesized that bacteremic sepsis during treatment for ALL contributes to long-term neurocognitive dysfunction and tested this hypothesis in a cohort study, using a propensity score–weighted model to adjust for potential confounders.3
Cheung YT, Eskind A, Inaba H, et al. Association of Bacteremic Sepsis With Long-term Neurocognitive Dysfunction in Pediatric Patients With Acute Lymphoblastic Leukemia. JAMA Pediatr. 2018;172(11):1092–1095. doi:10.1001/jamapediatrics.2018.2500
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