To the Editor We read with great interest the article by Poon et al1 showing that mothers of children with hypospadias may have higher level of polybrominated diphenyl ethers (PBDEs) exposures during pregnancy. The prevalence of hypospadias has increased in the past few decades worldwide and this study could partially explain the association between the global use of PBDEs for flame retardant and hypospadias. However, we still have some comments for the study methods and other potential factors for future analysis.
Chen C, Chen C. Association of Prenatal Exposures of Polybrominated Diphenyl Ethers With Hypospadias. JAMA Pediatr. 2019;173(1):106. doi:10.1001/jamapediatrics.2018.4049
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: