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JAMA Pediatrics Clinical Evidence Synopsis
December 28, 2018

Probiotics for Children With Recurrent Abdominal Pain

Author Affiliations
  • 1University of Exeter Medical School, Exeter, England
  • 2National Institute for Health Research Collaborations for Leadership in Applied Health Research and Care South West Peninsula, University of Exeter Medical School, Exeter, England
  • 3Bristol Royal Hospital for Children, Bristol, England
JAMA Pediatr. 2019;173(2):183-184. doi:10.1001/jamapediatrics.2018.4575

Clinical Question  Do dietary interventions, such as probiotics, improve pain in children with recurrent abdominal pain?

Clinical Application  Compared with placebo, children who were treated with probiotic preparations were more likely to experience improvement in pain in the short term (odds ratio, 1.63; 95% CI, 1.07-2.47), suggesting that clinicians could consider probiotics as part of a holistic management strategy in recurrent abdominal pain.

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