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Frey and colleagues conducted a noninferiority randomized clinical trial of 90 children who presented to emergency departments with pain due to traumatic limb injuries. They found that intranasal ketamine was noninferior to intranasal fentanyl for pain relief, with mean reductions in visual analog scale pain scores of 30.6 mm and 31.9 mm, respectively, at 30 minutes after intervention.
Miller and colleagues conducted a population-based study of 15 175 US children. They found that compared with later-born siblings of children without a diagnosis, later-born siblings of those with autism spectrum disorder (ASD) were more likely to receive a diagnosis of ASD or attention deficit/hyperactivity disorder (ADHD). In addition, compared with later-born siblings of children without a diagnosis, later-born siblings of children with ADHD were more likely to receive a diagnosis of ADHD or ASD.
Author Audio Interview
Using data from the 2016 National Survey of Children’s Health, Xu and colleagues found that among 43 032 US children aged 3 to 17 years, 2.79% received a diagnosis of autism spectrum disorder (ASD). Among 1115 children with current ASD, 43.3% were treated with behavioral treatment only, 6.9% with medication treatment only, 20.3% with both behavioral and medication treatments, and 29.5% with neither treatment.
Shaker and colleagues used Markov simulations of the Chicago Public Schools system (371 382 students). They found that the current policy (that schools maintain 2 undesignated stock twin-pack units that supplement additionally provided student-designated units) is cost-effective when total school epinephrine acquisition expenses do not exceed $338 per school per year. However, a universal (stock-only) model, without requiring student-designated units, provides superior value.
Continuing Medical Education
Highlights. JAMA Pediatr. 2019;173(2):115. doi:10.1001/jamapediatrics.2018.3477
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