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JAMA Network Clinical Guideline Synopsis
March 18, 2019

Management of Pediatric Gastroesophageal Reflux Disease

Author Affiliations
  • 1Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Weill Cornell Medicine, New York, New York
  • 2Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio
JAMA Pediatr. 2019;173(5):485-486. doi:10.1001/jamapediatrics.2019.0170

Gastroesophageal reflux (GER) is the passage of gastric contents into the esophagus, with or without regurgitation and vomiting. Gastroesophageal reflux disease (GERD) occurs when GER leads to troublesome symptoms or complications.1 The diagnosis of GERD in children increased more than 5-fold between 1999 and 2005 and the rise among infants has been even more significant.2 Symptoms include heartburn, regurgitation, and retrosternal or epigastric pain but can be vague.1 In infants, fussiness, back arching, and regurgitation are often attributed to GERD; however, regurgitation is common in healthy babies.