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March 25, 2019

Considerations to Guide Treatment Decisions for Infants Born Weighing Less Than 400 g

Author Affiliations
  • 1Children’s Mercy Kansas City, Kansas City, Missouri
JAMA Pediatr. 2019;173(5):418-419. doi:10.1001/jamapediatrics.2019.0177

In this issue of JAMA Pediatrics, Brumbaugh et al1 show that infants born weighing less than 400 g can survive. In this study, when such infants were admitted to neonatal intensive care units (NICUs) and actively treated, 26% survived to discharge. Survival for infants who were born at 24 weeks’ gestational age or older was nearly twice as high (32%) as the survival rate for infants born at 22 to 23 weeks’ gestational age (17%). Most survivors had chronic health problems and neurodevelopmental impairments (NDIs). So, should we try to save such infants?

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