In this issue of JAMA Pediatrics, Brumbaugh et al1 show that infants born weighing less than 400 g can survive. In this study, when such infants were admitted to neonatal intensive care units (NICUs) and actively treated, 26% survived to discharge. Survival for infants who were born at 24 weeks’ gestational age or older was nearly twice as high (32%) as the survival rate for infants born at 22 to 23 weeks’ gestational age (17%). Most survivors had chronic health problems and neurodevelopmental impairments (NDIs). So, should we try to save such infants?
Lantos JD. Considerations to Guide Treatment Decisions for Infants Born Weighing Less Than 400 g. JAMA Pediatr. 2019;173(5):418–419. doi:10.1001/jamapediatrics.2019.0177
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