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Comment & Response
March 25, 2019

Supplementing Essential Polyunsaturated Fatty Acids—A Matter of Respecting Fetal Development

Author Affiliations
  • 1Department of Neonatology, Children’s Hospital, Faculty of Medicine, Eberhard Karls University, Tübingen, Germany
  • 2Center for Pediatric Clinical Studies, Children’s Hospital, Faculty of Medicine, Eberhard Karls University, Tübingen, Germany
JAMA Pediatr. 2019;173(5):499-500. doi:10.1001/jamapediatrics.2019.0334

To the Editor In their randomized clinical trial, Keim et al1 describe the effects of 6 months’ supplementation with 200 mg per day each of docosahexaenoic acid (DHA) and arachidonic acid (AA) in toddlers born preterm on their neurocognitive outcome. The title focuses on DHA, whereas the study concept is cosupplementation with AA. Collins et al2 used DHA supplementation only, although they similarly refer to combined AA+DHA supplementation or maternal DHA supplementation with AA being transferred to the fetus from maternal sources.

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