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JAMA Pediatrics Clinical Evidence Synopsis
April 29, 2019

Glucocorticoids for Croup in Children

Author Affiliations
  • 1Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
  • 2Departments of Pediatrics, Emergency Medicine, and Physiology and Pharmacology, Cumming School of Medicine, the Alberta Children’s Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada
  • 3George & Fay Yee Centre for Health Care Innovation, Children’s Hospital Research Institute of Manitoba, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada
JAMA Pediatr. 2019;173(6):595-596. doi:10.1001/jamapediatrics.2019.0834
Abstract

Clinical Question  For children with croup, do glucocorticoids reduce clinical symptoms, minimize return visits and/or (re)admissions to the hospital, shorten lengths of stay, or reduce the need for additional treatments?

Bottom Line  Glucocorticoids reduce symptoms of croup at 2 hours and for at least 24 hours, reduce return visits to care, and shorten hospital stays by about 15 hours. Serious adverse events are infrequent.

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