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June 3, 2019

Cardiovascular Risk in Adults Born Preterm: Time to Act

Author Affiliations
  • 1Centre Hospitalier Universitaire Sainte-Justine Research Center, Department of Pediatrics, Université de Montréal, Montreal, Québec, Canada
JAMA Pediatr. 2019;173(8):720-721. doi:10.1001/jamapediatrics.2019.1324

Prematurity currently accounts for around 10% of births with improved survival rates observed over the past 40 years thanks to substantial advances in perinatal care. However, long-term cohort studies have shown that being born preterm is associated with increased risks of hypertension and glucose intolerance1-3 that may be associated with the observed higher incidence of cerebrovascular disease4 and death caused by cardiovascular disease in young adulthood in this vulnerable population.5 Whether this also translates into higher incidence of ischemic heart disease (IHD) has to date remained unclear because of the relatively young age of individuals born in the modern era of neonatology that started around the end of the 1980s and survival bias in those born before.