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Comment & Response
July 8, 2019

Implications of Gestational Weight Gain in Studies of Gestational Diabetes

Author Affiliations
  • 1Department of Endocrinology, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
  • 2Department of Obstetrics and Gynecology, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
JAMA Pediatr. Published online July 8, 2019. doi:10.1001/jamapediatrics.2019.2195

To the Editor A research article published in JAMA Pediatrics, “Associations of Maternal Diabetes and Body Mass Index With Offspring Birth Weight and Prematurity,”1 asserts that maternal insulin-treated diabetes and obesity in mothers with type 2 diabetes appeared to be associated with increased risks for the offspring being large for gestational age (LGA) and preterm births. Increased LGA risks were found also for mothers with diabetes with insulin treatment, with type 2 diabetes and gestational diabetes (GDM) not treated with insulin. In addition, prematurity rose for mothers with type 2 diabetes, independent of prepregnancy body mass index (BMI). Prepregnancy BMI, with no diabetes, was associated with the risk for LGA and prematurity.

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