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Research Letter
July 22, 2019

Association of Sleep Problems and Melatonin Use in School-aged Children

Author Affiliations
  • 1Department of Child and Adolescent Psychiatry, Erasmus University Medical Center–Sophia Children’s Hospital, Rotterdam, the Netherlands
  • 2The Generation R Study Group, Erasmus Medical Center, Rotterdam, the Netherlands
  • 3Department of Social and Behavioral Science, Harvard T. H. Chan School of Public Health, Boston, Massachusetts
  • 4Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands
JAMA Pediatr. Published online July 22, 2019. doi:10.1001/jamapediatrics.2019.2084

Sleep problems are reported in 25% of children and adolescents.1 Melatonin is available in many countries without a prescription and is often considered a pharmacologic strategy to treat sleep problems. However, no clinical guidelines are available, and effectiveness and long-term effects of melatonin use in children are largely unknown.1 Melatonin use has been estimated to be 1% in healthy children. Little is known about the association of objectively measured sleep with melatonin use in this population. We investigated melatonin use in school-aged children and its association with subjective sleep and objectively estimated sleep parameters.

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