[Skip to Content]
[Skip to Content Landing]
Views 113
Citations 0
Comment & Response
September 16, 2019

Albuterol and Pediatric Perioperative Respiratory Complications—Reply

Author Affiliations
  • 1Department of Anaesthesia and Pain Management, Perth Children’s Hospital, Perth, Australia
  • 2Medical School, The University of Western Australia, Perth, Australia
  • 3Telethon Kids Institute, Perth, Australia
  • 4School of Physiotherapy and Exercise Science, Curtin University, Perth, Australia
JAMA Pediatr. Published online September 16, 2019. doi:10.1001/jamapediatrics.2019.3188

In Reply We thank our colleagues for their interest in our study.1 We agree that many respiratory adverse events are common and minor and may have little effect on the patient’s immediate clinical care. However, bronchospasm and laryngospasm are known to be a major cause of perioperative cardiac arrests, unplanned intensive care unit admissions, and neurological damage following anesthesia. The composite of these respiratory adverse events allows a standardized approach to clinical trials and minimizes the potential for operator bias across treatment arms. We do acknowledge that different approaches to these composite events are used and that careful consideration should be given when comparing outcomes from different clinical trials. However, this does not invalidate the outcomes within any one research study.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words