Infection with human cytomegalovirus (CMV) is ubiquitous, with a global seroprevalence of approximately 85%.1 In all human history, most CMV infections have probably been acquired from breastfeeding. Hayes et al2 in 1972 demonstrated that CMV could be cultured in breast milk, and breastfeeding was proposed as a mechanism by which the virus could be transmitted to the neonate. Subsequent work showed that such postnatal infections are generally innocuous in full-term infants,3 in contrast to the potentially devastating neurodevelopmental and audiological consequences of CMV infections acquired in utero.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Schleiss MR. Breast Milk–Acquired Cytomegalovirus in Premature Infants: Uncertain Consequences and Unsolved Biological Questions. JAMA Pediatr. 2020;174(2):121–123. doi:10.1001/jamapediatrics.2019.4538
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: