Antibiotic administration negatively affects the microbiome by decreasing bacterial diversity, and this has been associated with allergic disease.1-3 Exposure to multiple classes of antibiotics may lead to even greater perturbations to the gut biome than 1 class alone. The purpose of this study is to determine whether exposure to multiple antibiotic classes in infancy is associated with a higher risk of developing allergic disease in early childhood.
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Zven SE, Susi A, Mitre E, Nylund CM. Association Between Use of Multiple Classes of Antibiotic in Infancy and Allergic Disease in Childhood. JAMA Pediatr. Published online December 20, 2019. doi:10.1001/jamapediatrics.2019.4794
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