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Research Letter
January 21, 2020

Rotavirus Vaccination and Type 1 Diabetes Risk Among US Children With Commercial Insurance

Author Affiliations
  • 1Division of Viral Diseases, US Centers for Disease Control and Prevention, Atlanta, Georgia
  • 2Maximus Federal, Contracting Agency to the Division of Viral Diseases, US Centers for Disease Control and Prevention, Atlanta, Georgia
  • 3Division of Diabetes Translation, US Centers for Disease Control and Prevention, Atlanta, Georgia
JAMA Pediatr. 2020;174(4):383-385. doi:10.1001/jamapediatrics.2019.5513

Rotavirus may precipitate type 1 diabetes (T1D).1,2 Thus, rotavirus vaccination may be associated with T1D. For example, incidence of T1D in Australian children younger than 5 years declined after rotavirus vaccine introduction.3 However, 2 Finnish studies4,5 showed no association of rotavirus vaccination with T1D risk in children 10 years and younger, although statistical power in these studies was limited. We compared T1D risk by rotavirus vaccination status among US children with commercial insurance.

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    1 Comment for this article
    Stop fooling around with epidemiology and start UNDERSTANDING MECHANISMS of vaccine adverse events
    vinu arumugham | Independent
    You claim: "We found no association between rotavirus vaccination and T1D"

    But the study below says:


    "After adjusting to residence area in Israel, the odds ratio for T1DM associated with full vaccination against rotavirus was 7.38 (95%: 1.19–45.62, P = 0.032). The results of the present study do not support the conclusion that childhood immunization with rotavirus vaccine is associated with reduced risk of T1DM."

    Where is the science here? You can cook anything you want with these worthless epidemiological studies.

    You should stop fooling around with epidemiology and start UNDERSTANDING MECHANISMS.

    of Medicine: Most epidemiological vaccine safety studies are useless

    As Dr. Kaslow says here at the Global Vaccine Safety Summit, focus on understanding mechanisms:

    Cancer immunology, bioinformatics and chemokine evidence link vaccines contaminated with animal proteins to autoimmune disease: a detailed look at Crohn's disease and Vitiligo