Anabolic-androgenic steroids are schedule III drugs that are often used without a prescription to increase muscle mass and tone for appearance or performance enhancement.1,2 Use of anabolic-androgenic steroids is associated with negative physiological (eg, cardiovascular, neuroendocrine, musculoskeletal, and renal) health outcomes.1 Anabolic-androgenic steroids are also associated with mood and substance-use disorders, aggression, and violence.1 The use of anabolic-androgenic steroids is frequently observed among adolescents in the United States and is more prevalent among adolescent boys (3.3% of boys reporting use) compared with adolescent girls (2.4% of girls reporting use) nationwide.3 Although the use of anabolic-androgenic steroids is cross-sectionally associated with legal performance-enhancing substances, including creatine monohydrate,1,2 there is a paucity of longitudinal data determining predictors of anabolic-androgenic steroid use. Here, we examine the longitudinal association between legal performance-enhancing substances and subsequent use of anabolic-androgenic steroids in a population-based cohort of young adults. We hypothesized that legal performance-enhancing substance use in young adulthood would be associated with subsequent anabolic-androgenic steroid use at 7-year follow-up.
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Nagata JM, Ganson KT, Gorrell S, Mitchison D, Murray SB. Association Between Legal Performance-Enhancing Substances and Use of Anabolic-Androgenic Steroids in Young Adults. JAMA Pediatr. Published online May 18, 2020. doi:10.1001/jamapediatrics.2020.0883
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