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Comment & Response
June 1, 2020

Multiple Classes of Antibiotic Use in Infancy and Allergic Disease in Childhood

Author Affiliations
  • 1Department of Epidemiology, Biostatistics, and Occupational Health, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
  • 2Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
  • 3Department of Ophthalmology and Visual Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
JAMA Pediatr. 2020;174(10):1002-1003. doi:10.1001/jamapediatrics.2020.0966

To the Editor We read with great interest the study by Zven et al,1 which examined whether exposure to antibiotics at infancy is associated with an increased risk of allergic diseases in childhood. Overall, the study showed an increased risk of allergic diseases with exposure to commonly prescribed antibiotics, with adjusted hazard ratios ranging from 1.06 to 1.30 for 5 different classes of antibiotics. However, some potential sources of biases should be taken into consideration when interpreting these results.

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