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Comment & Response
May 26, 2020

More Details Needed on Association of Placental Weight With Risk of Neonatal Death—Reply

Author Affiliations
  • 1Department of Obstetrics and Gynecology, Akershus University Hospital, Lørenskog, Norway
  • 2Institute of Clinical Medicine, University of Oslo, Oslo, Norway
  • 3Department of Pediatric Research, Oslo University Hospital, University of Oslo, Oslo, Norway
JAMA Pediatr. 2020;174(9):906. doi:10.1001/jamapediatrics.2020.0975

In Reply We thank Zhang et al for the interest in our article, “Placental Weight and Risk of Neonatal Death.”1 They address concerns about the validity of our results. First, they ask whether the age of the mother could have biased the results because both placental weight and the risk of neonatal death are influenced by maternal age. In our study, we made adjustment for maternal age. Thus, the estimated association of placental weight with neonatal death is independent of maternal age. We could not study whether our results differ across maternal age groups. We did not have statistical power to perform such analyses, despite our large study sample.

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