In Reply We thank Zhang et al for the interest in our article, “Placental Weight and Risk of Neonatal Death.”1 They address concerns about the validity of our results. First, they ask whether the age of the mother could have biased the results because both placental weight and the risk of neonatal death are influenced by maternal age. In our study, we made adjustment for maternal age. Thus, the estimated association of placental weight with neonatal death is independent of maternal age. We could not study whether our results differ across maternal age groups. We did not have statistical power to perform such analyses, despite our large study sample.
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Dypvik J, Saugstad OD, Eskild A. More Details Needed on Association of Placental Weight With Risk of Neonatal Death—Reply. JAMA Pediatr. 2020;174(9):906. doi:10.1001/jamapediatrics.2020.0975
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