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JAMA Network Clinical Guideline Synopsis
June 22, 2020

Short-term Treatment of Migraine in Children and Adolescents

Author Affiliations
  • 1Texas Children’s Hospital Pediatric Headache Clinic, Section of Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine, Houston
  • 2Pediatric Headache Center, Dell Medical School, Department of Neurology, University of Texas at Austin, Austin
JAMA Pediatr. Published online June 22, 2020. doi:10.1001/jamapediatrics.2020.1422

Migraine is a primary headache disorder diagnosed in children and adolescents with recurrent attacks of headache of moderate to severe intensity, typically bilaterally, with a throbbing quality, duration of 2 to 72 hours, and associated sensitivity to sensory stimuli, movement sensitivity, and potential for nausea and vomiting. Pediatric migraine is a common and potentially disabling disorder with an 8% to 24% prevalence in school-aged children.2 More than one-quarter of children with migraine report associated moderate or severe disability.3 Migraine may negatively affect school attendance, school performance, peer relationships, family dynamics, and mood. Migraine, when ineffectively treated, may result in transformation to a more bothersome chronic pain disorder.4

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