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Comment & Response
July 13, 2020

Increase in Incidence of Neonatal Abstinence Syndrome Among in-Hospital Birth in the United States—Reply

Author Affiliations
  • 1Division of Overdose Prevention, National Center for Injury Prevention and Control, US Centers for Disease Control and Prevention, Atlanta, Georgia
  • 2Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, US Centers for Disease Control and Prevention, Atlanta, Georgia
  • 3Public Health Service, Commissioned Corps, Rockville, Maryland
JAMA Pediatr. Published online July 13, 2020. doi:10.1001/jamapediatrics.2020.1873

In Reply We appreciate Ramphul et al sharing estimates of the 2012 rate of in-hospital births with a neonatal abstinence syndrome (NAS) diagnosis. In our study1 of 2016 national incidence and cost estimates for in-hospital births with a NAS diagnosis, we did not make direct comparisons with earlier estimates2 owing to the 2015 transition from the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) to International Statistical Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) and because earlier studies may not have limited the sample to in-hospital births.

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